1,1-Dimethylhydrazine → HCID 59448138, compound

Participants

Reaction Steps

As described for example 28, 3-(3-butyl-5-methyl-isoxazol-4-ylmethoxy)-isoxazole-5-carboxylic acid methyl ester (110 mg, 0.37 mmol), was converted using N,N-dimethylhydrazine (90 mg, 1.5 mmol), instead of isopropyl amine, to the title compound (120 mg, 99%) which was obtained as a colourless oil after purification by chromatography (silica, dichloromethane:methanol=1:0 to 9:1). MS: m/e=323.3 [M+H]+.

Provenance & Evidence