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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1921035Generated: October 26, 2026

1-Methylindole-2-carboxaldehyde → 3,4-Dimethyl-2-(methylaminomethyl)thieno[2,3-b]thiophene

https://huagongshe.com/reaction/1921035

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methylindole-2-carboxaldehydeHCID 267164—
Reactant3,4-Dimethylthieno[2,3-B]Thiophene-2-CarbaldehydeHCID 2778771—
Product3,4-Dimethyl-2-(methylaminomethyl)thieno[2,3-b]thiopheneHCID 2259375653%

Reaction Steps

According to the procedure of Preparation 24 (a), except substituting 3,4-dimethylthieno[2,3-b]thiophene-2-carboxaldehyde (0.5 g, 2.5 mmole) for the 1-methylindole-2-carboxaldehyde, the title compound (0.28 g, 53%) was prepared as a colorless oil: MS (ES) m/e 212 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08173646B2
Source datasetuspto-grants-2012_05
ORD IDord-5e55740b78644ed5827c445838b70bdb
Source noteuspto-grants-2012_05