HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-dimethyl-1H-indole-2-carbaldehyde → 2,3-dihydro-8-(methylaminomethyl)-1H-3a-azacyclopenta[a]indene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-dimethyl-1H-indole-2-carbaldehyde | HCID 2771468 | — |
| Reactant | 2,3-dihydro-1H-3a-azacyclopenta[a]indene-8-carboxaldehyde | HCID 5323989 | — |
| Product | 2,3-dihydro-8-(methylaminomethyl)-1H-3a-azacyclopenta[a]indene | HCID 22139048 | 54% |
Reaction Steps
According to the procedure of Preparation 40 (c), except substituting 2,3-dihydro-1H-3a-azacyclopenta[a]indene-8-carboxaldehyde (0.17 g, 0.92 mmole) for the 1,3-dimethyl-1H-indole-2-carboxaldehyde, the title compound (0.1 g, 54%) was prepared as a yellow oil: MS (ES) m/e 201 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08173646B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-4c7cbe9268a14816aae1d24a87b218e3 |
| Source note | uspto-grants-2012_05 |