HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bis(2-chloroethyl)amine → N-[2-Oxo-8-(piperazin-1-yl)-2H-1-benzopyran-3-yl]acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bis(2-chloroethyl)amine | HCID 9533 | — |
| Reactant | N-(8-Amino-2-oxo-2H-1-benzopyran-3-yl)acetamide | HCID 21792250 | — |
| Product | N-[2-Oxo-8-(piperazin-1-yl)-2H-1-benzopyran-3-yl]acetamide | HCID 59427368 | — |
Reaction Steps
Step 4 was the alkylation of N-(8-amino-2-oxo-2H-1-benzopyran-3-yl)-acetamide (4*) with bis-chloroethylamine yielding N-(8-(1-piperazinyl)-2-oxo-2H-1-benzopyran-3-yl-)acetamide (5*).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08173660B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-df630dbea199459585673af5ab3e9486 |
| Source note | uspto-grants-2012_05 |