HCID 86626331, compound → HCID 86626332, compound

Participants

Reaction Steps

To a solution of 2-nitro-4-[4-(2,2,2-trifluoro-acetyl)-piperazin-1-yl]-benzoic acid tert-butyl ester (1.70 g, 4.22 mmol) in dichloromethane (25 mL) trifluoroacetic acid (5 mL) was added. The mixture was stirred at room temperature for 2 h, and then evaporated to give the title compound as yellow solid. 1H-NMR (400 MHz), δ (ppm, DMSO-d6): 13.21 (bs, 1H), 7.78 (d, J=8.9 Hz, 1H), 7.31 (d, J=2.5 Hz, 1H), 7.17 (dd, J1=8.9 Hz, J2=2.5 Hz, 1H), 3.74 (m, 4H), 3.56 (m, 4H).

Provenance & Evidence