HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86619741, compound → HCID 59279582, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86619741 | HCID 86619741 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 59279582 | HCID 59279582 | — |
Reaction Steps
A mixture of [4-bromo-7-chloro-3-(2-methoxy-2-oxoethyl)-1H-pyrrolo[2,3-c]pyridin-1-yl]acetic acid from Step E (27.0 mg, 0.075 mmol) and 10% Pd/C (10 mg) in MeOH (5 mL) was stirred under an atmosphere of hydrogen (ca.1 atm) for 2 h. The mixture was filtered through a pad of Celite, washing with MeOH, and the filtrate was concentrated in vacuo to give the title compound. MS: m/z=249 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08173655B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-5dd8cac6e72847b4b41e10aaef737c82 |
| Source note | uspto-grants-2012_05 |