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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1921221Generated: October 29, 2026

HCID 86619741, compound → HCID 59279582, compound

https://huagongshe.com/reaction/1921221

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86619741HCID 86619741—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 59279582HCID 59279582—

Reaction Steps

A mixture of [4-bromo-7-chloro-3-(2-methoxy-2-oxoethyl)-1H-pyrrolo[2,3-c]pyridin-1-yl]acetic acid from Step E (27.0 mg, 0.075 mmol) and 10% Pd/C (10 mg) in MeOH (5 mL) was stirred under an atmosphere of hydrogen (ca.1 atm) for 2 h. The mixture was filtered through a pad of Celite, washing with MeOH, and the filtrate was concentrated in vacuo to give the title compound. MS: m/z=249 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08173655B2
Source datasetuspto-grants-2012_05
ORD IDord-5dd8cac6e72847b4b41e10aaef737c82
Source noteuspto-grants-2012_05