HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 86610355, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2-Pyridinemethanamine | HCID 19509 | — |
| Reactant | 5-(5-Ethyl-2-methyl-6-oxo-1,6-dihydropyridin-3-yl)thiophene-2-sulfonyl chloride | HCID 86610352 | — |
| Product | HCID 86610355 | HCID 86610355 | 38% |
Reaction Steps
5-(5-Ethyl-2-methyl-6-oxo-1,6-dihydropyridin-3-yl)thiophene-2-sulfonyl chloride is reacted with (pyridin-2-yl)methylamine as described in Step 5, Example 24 and the resulting sulfonamide is converted to hydrochloride following the procedures as set forth in Step 6, Example 24 to give the title compound as a solid (38% yield). LC/MS: RT 2.28 min; me 390 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08173682B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-d9324ed33bf14099a021968fff25e12c |
| Source note | uspto-grants-2012_05 |