Hydrochloric Acid → HCID 11704971, compound

Participants

Reaction Steps

5-(5-Ethyl-2-methyl-6-oxo-1,6-dihydropyridin-3-yl)thiophene-2-sulfonyl chloride is reacted with [2-(1-methylpyrrolidin-2-yl)ethyl]amine as described in Step 5, Example 24 and the resulting product is subsequently converted to hydrochloride to give the title compound as a solid (70% yield). LC/MS: RT 2.03 min; m/e 410 (M+H); 1H NMR (δ, ppm): 11.84 (1H, s), 8.05 (1H, t), 7.58 (1H, d), 7.33 (1H, s); 7.17 (1H, d), 3.37 (1H), 3.01 (4H), 2.75 (3H), 2.39 (2H, q), 2.32 (3H, s), 1.60 (6H, m), 1.10 (3H, t).

Provenance & Evidence