1H-Imidazole-1-propanamine → HCID 71082922, compound

HRID 1921411Notes

Reaction equation

HRID 1921411 reaction equation
[CH2:1]([C:3]1[C:8](=[O:9])[NH:7][C:6]([CH3:10])=[C:5]([C:11]2[O:15][C:14]([S:16]([Cl:19])(=[O:18])=[O:17])=[CH:13][CH:12]=2)[CH:4]=1)[CH3:2].[N:20]1([CH2:25][CH2:26][CH2:27][NH2:28])[CH:24]=[CH:23][N:22]=[CH:21]1>>[ClH:19].[N:20]1([CH2:25][CH2:26][CH2:27][NH:28][S:16]([C:14]2[O:15][C:11]([C:5]3[CH:4]=[C:3]([CH2:1][CH3:2])[C:8](=[O:9])[NH:7][C:6]=3[CH3:10])=[CH:12][CH:13]=2)(=[O:18])=[O:17])[CH:24]=[CH:23][N:22]=[CH:21]1

Participants

3

Reactant 2

HCID 787361H-Imidazole-1-propanamineHCID 86610360HCID 86610360, compound

Product 1

HCID 71082922HCID 71082922, compoundYield 41%

Procedure

5-(5-Ethyl-2-methyl-6-oxo-1,6-dihydropyridin-3-yl)furan-2-sulfonyl chloride is reacted with (3-imidazol-1-yl)propylamine as described in Steps 5 and 6, Example 24 to give the title compound as a solid (41% yield). LC/MS: RT 1.54 min; m/e 391 (M+H).

Sources & evidence

ORD record
ord-6e491a89e5ab45a29482c3ddfee195ef
Source dataset
uspto-grants-2012_05
Patent number
US08173682B2

Reaction notes

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