3-Pyridinemethanamine → HCID 86610361, compound

HRID 1921412Notes

Reaction equation

[CH2:1]([C:3]1[C:8](=[O:9])[NH:7][C:6]([CH3:10])=[C:5]([C:11]2[O:15][C:14]([S:16]([Cl:19])(=[O:18])=[O:17])=[CH:13][CH:12]=2)[CH:4]=1)[CH3:2].[N:20]1[CH:25]=[CH:24][CH:23]=[C:22]([CH2:26][NH2:27])[CH:21]=1>>[ClH:19].[N:20]1[CH:25]=[CH:24][CH:23]=[C:22]([CH2:26][NH:27][S:16]([C:14]2[O:15][C:11]([C:5]3[CH:4]=[C:3]([CH2:1][CH3:2])[C:8](=[O:9])[NH:7][C:6]=3[CH3:10])=[CH:12][CH:13]=2)(=[O:18])=[O:17])[CH:21]=1

Participants

Reactant 2

HCID 310183-Pyridinemethanamine

HCID 86610360HCID 86610360, compound

Product 1

HCID 86610361HCID 86610361, compoundYield 10%

Procedure

5-(5-Ethyl-2-methyl-6-oxo-1,6-dihydropyridin-3-yl)furan-2-sulfonyl chloride is reacted with (pyridin-3-yl)methylamine as described in Steps 5 and 6, Example 24 to give the title compound as a solid (10% yield). LC/MS: RT 2.05 min; m/e 374 (M+H).

Sources & evidence

ORD record: ord-ce12a28b98e9416bbcf5fcbb10c65edf
Source dataset: uspto-grants-2012_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08173682B2

Reaction notes

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