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HRID1921426

反应详情

EQUATION

反应方程式

HRID 1921426 的结构方程式

REACTANTS

反应物

2
结构：C1COCCN1
HCID8083

Morpholine

C4H9NO

结构：CCc1cc(-c2ccc(S(=O)(=O)Cl)s2)c(C)[nH]c1=O
HCID86610352

未命名化合物

PRODUCTS

生成物

1
结构：CCc1cc(-c2ccc(S(=O)(=O)N3CCOCC3)s2)c(C)[nH]c1=O
HCID58808676

未命名化合物

收率 57.4%

PROCEDURE

实验过程

5-(5-Ethyl-2-methyl-6-oxo-1,6-dihydropyridin-3-yl)thiophene-2-sulfonyl chloride is reacted with morpholine as described in Step 5, Example 24 to give the title compound as a solid (57.4% yield). LC/MS: RT 2.72 min; m/e 369 (M+H); 1H NMR (δ, ppm): 11.8 (1H, s), 7.6 (1H, d); 7.4 (1H, d); 7.3 (1H, d), 3.7 (4H, m), 2.95 (4H, s), 2.4 (2H, q), 2.36 (3H, s), 1.05 (3H, t).