1-Piperazinecarboxylic acid, ethyl ester → HCID 58808527, compound

Participants

Reaction Steps

5-(5-Ethyl-2-methyl-6-oxo-1,6-dihydropyridin-3-yl)thiophene-2-sulfonyl chloride is reacted with ethyl piperazine-1-carboxylate as described in Step 5, Example 24 to give the title compound as a solid (60.2% yield). LC/MS: RT 2.93 min; m/e 440 (M+H); 1H NMR (δ, ppm): 11.8 (1H, s), 7.6 (1H, d); 7.4 (1H, s); 7.3 (1H, d), 4.0 (2H, t), 3.5 (4H, m), 3.0 (4H, m), 2.4 (2H, q), 2.36 (3H, s), 1.08 (6H, m).

Provenance & Evidence