N,N-Diethyl-1,3-propanediamine → HCID 71082844, compound

Participants

Reaction Steps

5-(5-Ethyl-2-methyl-6-oxo-1,6-dihydropyridin-3-yl)thiophene-2-sulfonyl chloride is reacted with N,N-diethyl-propane-1,3-diamine as described in Steps 5 and 6, Example 24 to give the title compound as an orange solid (50% yield). LC/MS: RT: 2.03 min; m/e 412 (M+H); 1H NMR (δ, ppm): 11.86 (1H, s), 10.07 (1H, s), 8.05 (1H, t), 7.56 (1H, d), 7.34 (1H, s), 7.19 (1H, d), 2.93-3.58 (8H, m), 2.40 (2H, q), 2.32 (3H, s), 1.82 (2H, m), 1.19 (6H, t), 1.10 (3H, t).

Provenance & Evidence