2-(Pyridin-3-yl)ethan-1-amine → HCID 71082914, compound

Participants

Reaction Steps

5-(5-Ethyl-2-methyl-6-oxo-1,6-dihydropyridin-3-yl)thiophene-2-sulfonyl chloride is reacted with 2-pyridin-3-yl-ethylamine as described in Steps 5 and 6, Example 24 to give the title compound as a cream-yellow solid (31% yield). LC/MS: RT 2.02 min, m/e 404 (M+H); 1H NMR (δ, ppm): 11.85 (1H, s), 8.79-8.82 (2H, m), 8.47 (1H, d), 7.98-8.08 (2H, m), 7.52 (1H, dd), 7.33 (1H, s), 7.15 (1H, dd), 3.25 (2H, dt), 2.98 (2H, t), 2.41 (2H, q), 2.31 (3H, s), 1.10 (3H, t).

Provenance & Evidence