1H-Benzimidazole-2-methanamine → HCID 11525549, compound

Participants

Reaction Steps

5-(5-Ethyl-2-methyl-6-oxo-1,6-dihydropyridin-3-yl)thiophene-2-sulfonyl chloride is reacted with (1H-benzoimidazol-2-yl)methylamine as described in Step 5, Example 24 to give the title compound as a yellow solid (44% yield). LC/MS: RT 2.10 min; m/e 429 (M+H); 1H NMR (δ, ppm): 11.80 (1H, br), 9.17 (1H, t), 7.80 (2H, m), 7.70 (1H, d), 7.50 (2H, m), 7.21 (1H, s), 7.12 (1H, d), 4.65 (3H, m), 2.40 (2H, q), 2.28 (3H, s), 1.10 (3H, t).

Provenance & Evidence