N-(2-aminoethyl)acetamide → HCID 11639567, compound

Participants

Reaction Steps

5-(5-Ethyl-2-methyl-6-oxo-1,6-dihydropyridin-3-yl)thiophene-2-sulfonyl chloride is reacted with N-(2-aminoethyl)acetamide as described in Step 5, Example 24 to give the title compound as a yellow solid (71% yield). LC/MS: RT 3.60 min; m/e 384 (M+H); 1H NMR (CDCl3, δ, ppm): 11.53 (1H, br), 7.50 (1H, d), 7.25 (1H, s), 6.90 (1H, d), 6.13 (1H, br), 5.90 (1H, br), 3.42 (31H, m), 3.20 (2H, m), 2.40-2.60 (5H, m), 2.00 (3H, m), 1.20 (3H, t).

Provenance & Evidence