Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1921459Generated: October 26, 2026

1H-Indol-3-Ylmethanamine → 5-(5-Ethyl-2-methyl-6-oxo-1,6-dihydro-pyridin-3-yl)-thiophene-2-sulfonic acid (1H-indol-3-ylmethyl)-amide

https://huagongshe.com/reaction/1921459

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-Indol-3-YlmethanamineHCID 472107—
Reactant5-(5-Ethyl-2-methyl-6-oxo-1,6-dihydropyridin-3-yl)thiophene-2-sulfonyl chlorideHCID 86610352—
Product5-(5-Ethyl-2-methyl-6-oxo-1,6-dihydro-pyridin-3-yl)-thiophene-2-sulfonic acid (1H-indol-3-ylmethyl)-amideHCID 58808660—

Reaction Steps

5-(5-Ethyl-2-methyl-6-oxo-1,6-dihydropyridin-3-yl)thiophene-2-sulfonyl chloride is reacted with 1H-indol-3-ylmethyl amine as described in Step 5, Example 24 to give the title compound. MS: m/e 428 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08173682B2
Source datasetuspto-grants-2012_05
ORD IDord-f5ac5140f63c4ebc855e517d6c6ebefe
Source noteuspto-grants-2012_05