1-Acetylpiperazine → HCID 58808759, compound

HRID 1921471Notes

Reaction equation

[CH2:1]([C:3]1[C:8](=[O:9])[NH:7][C:6]([CH3:10])=[C:5]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([CH:17]=O)[N:12]=2)[CH:4]=1)[CH3:2].[C:19]([N:22]1[CH2:27][CH2:26][NH:25][CH2:24][CH2:23]1)(=[O:21])[CH3:20]>>[C:19]([N:22]1[CH2:27][CH2:26][N:25]([CH2:17][C:13]2[N:12]=[C:11]([C:5]3[CH:4]=[C:3]([CH2:1][CH3:2])[C:8](=[O:9])[NH:7][C:6]=3[CH3:10])[CH:16]=[CH:15][CH:14]=2)[CH2:24][CH2:23]1)(=[O:21])[CH3:20]

Participants

Reactant 2

HCID 837951-Acetylpiperazine

HCID 58808670HCID 58808670, compound

Product 1

HCID 58808759HCID 58808759, compound

Procedure

5′-Ethyl-2′-methyl-6′-oxo-1′,6′-dihydro-[2,3′]bipyridinyl-6-carbaldehyde prepared in accordance with PREPARATION 11 is reacted with 4-acetylpiperazine as described in Method A, Example 123 to give the title compound. MS: m/e=355 (M+H).

Sources & evidence

ORD record: ord-050fbd6773dd4deea09cfc44f4e72df7
Source dataset: uspto-grants-2012_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08173682B2

Reaction notes

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