1-Cyclopropyl-1-(3-pyridyl)methylamine → HCID 58808691, compound

HRID 1921498Notes

Reaction equation

HRID 1921498 reaction equation
[CH2:1]([C:3]1[C:8](=[O:9])[NH:7][C:6]([CH3:10])=[C:5]([C:11]2[CH:12]=[N:13][CH:14]=[C:15]([C:17]([OH:19])=O)[CH:16]=2)[CH:4]=1)[CH3:2].[CH:20]1([CH:23]([NH2:30])[C:24]2[CH:25]=[N:26][CH:27]=[CH:28][CH:29]=2)[CH2:22][CH2:21]1>>[CH:20]1([CH:23]([NH:30][C:17]([C:15]2[CH:16]=[C:11]([C:5]3[CH:4]=[C:3]([CH2:1][CH3:2])[C:8](=[O:9])[NH:7][C:6]=3[CH3:10])[CH:12]=[N:13][CH:14]=2)=[O:19])[C:24]2[CH:25]=[N:26][CH:27]=[CH:28][CH:29]=2)[CH2:21][CH2:22]1

Participants

3

Reactant 2

HCID 51533491-Cyclopropyl-1-(3-pyridyl)methylamineHCID 588087025'-Ethyl-2'-methyl-6'-oxo-1',6'-dihydro-[3,3']bipyridinyl-5-carboxylic acid

Product 1

HCID 58808691HCID 58808691, compound

Procedure

Method 1, Example 205 is substantially repeated except for utilizing 5′-ethyl-2′-methyl-6′-oxo-1′,6′-dihydro-[3,3′]bipyridinyl-5-carboxylic acid and (cyclopropyl-pyridin-3-yl-methyl)-amine to afford the title compound. MS: m/e=389 (M+H).

Sources & evidence

ORD record
ord-d336ad34dc3843f79a1471a67340b005
Source dataset
uspto-grants-2012_05
Patent number
US08173682B2

Reaction notes

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