1,3-Thiazol-2-ylmethanamine → HCID 58808625, compound

HRID 1921518Notes

Reaction equation

HRID 1921518 reaction equation
[CH2:1]([C:3]1[C:8](=[O:9])[NH:7][C:6]([CH3:10])=[C:5]([C:11]2[CH:12]=[N:13][CH:14]=[C:15]([C:17]([OH:19])=O)[CH:16]=2)[CH:4]=1)[CH3:2].[S:20]1[CH:24]=[CH:23][N:22]=[C:21]1[CH2:25][NH2:26]>>[S:20]1[CH:24]=[CH:23][N:22]=[C:21]1[CH2:25][NH:26][C:17]([C:15]1[CH:16]=[C:11]([C:5]2[CH:4]=[C:3]([CH2:1][CH3:2])[C:8](=[O:9])[NH:7][C:6]=2[CH3:10])[CH:12]=[N:13][CH:14]=1)=[O:19]

Participants

3

Reactant 2

HCID 27565071,3-Thiazol-2-ylmethanamineHCID 588087025'-Ethyl-2'-methyl-6'-oxo-1',6'-dihydro-[3,3']bipyridinyl-5-carboxylic acid

Product 1

HCID 58808625HCID 58808625, compound

Procedure

Method 1, Example 205 is substantially repeated except for utilizing 5′-ethyl-2′-methyl-6′-oxo-1′,6′-dihydro-[3,3′]bipyridinyl-5-carboxylic acid and (thiazol-2-ylmethyl)-amine to afford the title compound. MS: m/e=355 (M+H).

Sources & evidence

ORD record
ord-ee248f76f6d743ad80783d3e46cda978
Source dataset
uspto-grants-2012_05
Patent number
US08173682B2

Reaction notes

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