HCID 22052470, compound → HCID 58808770, compound

HRID 1921525Notes

Reaction equation

HRID 1921525 reaction equation
[CH2:1]([C:3]1[C:8](=[O:9])[NH:7][C:6]([CH3:10])=[C:5]([C:11]2[CH:12]=[N:13][CH:14]=[C:15]([C:17]([OH:19])=O)[CH:16]=2)[CH:4]=1)[CH3:2].[N:20]1[CH:25]=[CH:24][C:23]([C:26]2[CH2:30][CH:29]([CH2:31][NH2:32])[O:28][N:27]=2)=[CH:22][CH:21]=1>>[N:20]1[CH:21]=[CH:22][C:23]([C:26]2[CH2:30][CH:29]([CH2:31][NH:32][C:17]([C:15]3[CH:16]=[C:11]([C:5]4[CH:4]=[C:3]([CH2:1][CH3:2])[C:8](=[O:9])[NH:7][C:6]=4[CH3:10])[CH:12]=[N:13][CH:14]=3)=[O:19])[O:28][N:27]=2)=[CH:24][CH:25]=1

Participants

3

Reactant 2

HCID 22052470HCID 22052470, compoundHCID 588087025'-Ethyl-2'-methyl-6'-oxo-1',6'-dihydro-[3,3']bipyridinyl-5-carboxylic acid

Product 1

HCID 58808770HCID 58808770, compound

Procedure

Method 1, Example 205 is substantially repeated except for utilizing 5′-ethyl-2′-methyl-6′-oxo-1′,6′-dihydro-[3,3′]bipyridinyl-5-carboxylic acid and (3-pyridin-4-yl-4,5-dihydro-isoxazol-5-ylmethyl)-amine to afford the title compound. MS: m/e=418 (M+H).

Sources & evidence

ORD record
ord-f13905a60a85487bb84cbb132939725f
Source dataset
uspto-grants-2012_05
Patent number
US08173682B2

Reaction notes

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