3-Isoxazolamine, 5-(1,1-dimethylethyl)- → HCID 58808597, compound

HRID 1921527Notes

Reaction equation

HRID 1921527 reaction equation
[CH2:1]([C:3]1[C:8](=[O:9])[NH:7][C:6]([CH3:10])=[C:5]([C:11]2[CH:12]=[N:13][CH:14]=[C:15]([C:17]([OH:19])=O)[CH:16]=2)[CH:4]=1)[CH3:2].[C:20]([C:24]1[O:28][N:27]=[C:26]([NH2:29])[CH:25]=1)([CH3:23])([CH3:22])[CH3:21]>>[C:20]([C:24]1[O:28][N:27]=[C:26]([NH:29][C:17]([C:15]2[CH:16]=[C:11]([C:5]3[CH:4]=[C:3]([CH2:1][CH3:2])[C:8](=[O:9])[NH:7][C:6]=3[CH3:10])[CH:12]=[N:13][CH:14]=2)=[O:19])[CH:25]=1)([CH3:23])([CH3:22])[CH3:21]

Participants

3

Reactant 2

HCID 1714733-Isoxazolamine, 5-(1,1-dimethylethyl)-HCID 588087025'-Ethyl-2'-methyl-6'-oxo-1',6'-dihydro-[3,3']bipyridinyl-5-carboxylic acid

Product 1

HCID 58808597HCID 58808597, compound

Procedure

Method 1, Example 205 is substantially repeated except for utilizing 5′-ethyl-2′-methyl-6′-oxo-1′,6′-dihydro-[3,3′]bipyridinyl-5-carboxylic acid and (5-tert-butyl-isoxazol-3-yl)-amine to afford the title compound. MS: m/e=381 (M+H).

Sources & evidence

ORD record
ord-d7df20be74664c24aa4afba18136b4f4
Source dataset
uspto-grants-2012_05
Patent number
US08173682B2

Reaction notes

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