Dimethylamine → HCID 58808523, compound

HRID 1921538Notes

Reaction equation

HRID 1921538 reaction equation
[CH2:1]([C:3]1[C:8](=[O:9])[NH:7][C:6]([CH3:10])=[C:5]([C:11]2[O:15][C:14]([C:16]([OH:18])=O)=[CH:13][CH:12]=2)[CH:4]=1)[CH3:2].[CH3:19][NH:20][CH3:21]>>[CH3:19][N:20]([CH3:21])[C:16]([C:14]1[O:15][C:11]([C:5]2[CH:4]=[C:3]([CH2:1][CH3:2])[C:8](=[O:9])[NH:7][C:6]=2[CH3:10])=[CH:12][CH:13]=1)=[O:18]

Participants

3

Reactant 2

HCID 674DimethylamineHCID 674924175-(5-Ethyl-2-methyl-6-oxo-1,6-dihydropyridin-3-yl)furan-2-carboxylic acid

Product 1

HCID 58808523HCID 58808523, compoundYield 50%

Procedure

Method 1, Example 205 is substantially repeated except for utilizing 5-(5-ethyl-2-methyl-6-oxo-1,6-dihydro-pyridin-3-yl)-furan-2-carboxylic acid and dimethylamine to afford the title compound (50% yield). LC/MS: RT 2.3 min; m/e 275 (M+H).

Sources & evidence

ORD record
ord-7891d34da2d04b36a88bbce17ca95ccb
Source dataset
uspto-grants-2012_05
Patent number
US08173682B2

Reaction notes

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