Dimethylamine → HCID 58808666, compound

HRID 1921540Notes

Reaction equation

HRID 1921540 reaction equation
[CH2:1]([C:3]1[C:8](=[O:9])[NH:7][C:6]([CH3:10])=[C:5]([C:11]2[S:15][C:14]([C:16]([OH:18])=O)=[CH:13][CH:12]=2)[CH:4]=1)[CH3:2].[CH3:19][NH:20][CH3:21]>>[CH3:19][N:20]([CH3:21])[C:16]([C:14]1[S:15][C:11]([C:5]2[CH:4]=[C:3]([CH2:1][CH3:2])[C:8](=[O:9])[NH:7][C:6]=2[CH3:10])=[CH:12][CH:13]=1)=[O:18]

Participants

3

Reactant 2

HCID 674DimethylamineHCID 67492337HCID 67492337, compound

Product 1

HCID 58808666HCID 58808666, compoundYield 77%

Procedure

Method 1, Example 205 is substantially repeated except for utilizing 5-(5-ethyl-2-methyl-6-oxo-1,6-dihydro-pyridin-3-yl)-thiophene-2-carboxylic acid and dimethylamine to afford the title compound (77% yield). LC/MS: RT 2.44 min; m/e 291 (M+H).

Sources & evidence

ORD record
ord-d87c430f29ee417abb72f57305a5e571
Source dataset
uspto-grants-2012_05
Patent number
US08173682B2

Reaction notes

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