Benzoyl chloride → HCID 58808684, compound

HRID 1921550Notes

Reaction equation

[NH2:1][CH2:2][C:3]1[O:7][C:6]([C:8]2[CH:9]=[C:10]([CH2:16][CH3:17])[C:11](=[O:15])[NH:12][C:13]=2[CH3:14])=[CH:5][CH:4]=1.[C:18](Cl)(=[O:25])[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[CH2:16]([C:10]1[C:11](=[O:15])[NH:12][C:13]([CH3:14])=[C:8]([C:6]2[O:7][C:3]([CH2:2][NH:1][C:18](=[O:25])[C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)=[CH:4][CH:5]=2)[CH:9]=1)[CH3:17]

Participants

Reactant 2

HCID 7412Benzoyl chloride

HCID 588087185-(5-aminomethylfuran-2-yl)-3-ethyl-6-methyl-1H-pyridin-2-one

Product 1

HCID 58808684HCID 58808684, compound

Procedure

Example 269 is substantially repeated except for utilizing 5-(5-aminomethylfuran-2-yl)-3-ethyl-6-methyl-1H-pyridin-2-one and benzoyl chloride to afford the title compound. MS: m/e=337 (M+H).

Sources & evidence

ORD record: ord-3ec08b065dcb4003b6da5adae3081c4d
Source dataset: uspto-grants-2012_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08173682B2

Reaction notes

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