p-Anisoyl chloride → HCID 58808566, compound

HRID 1921551Notes

Reaction equation

HRID 1921551 reaction equation
[NH2:1][CH2:2][C:3]1[O:7][C:6]([C:8]2[CH:9]=[C:10]([CH2:16][CH3:17])[C:11](=[O:15])[NH:12][C:13]=2[CH3:14])=[CH:5][CH:4]=1.[CH3:18][O:19][C:20]1[CH:28]=[CH:27][C:23]([C:24](Cl)=[O:25])=[CH:22][CH:21]=1>>[CH2:16]([C:10]1[C:11](=[O:15])[NH:12][C:13]([CH3:14])=[C:8]([C:6]2[O:7][C:3]([CH2:2][NH:1][C:24](=[O:25])[C:23]3[CH:27]=[CH:28][C:20]([O:19][CH3:18])=[CH:21][CH:22]=3)=[CH:4][CH:5]=2)[CH:9]=1)[CH3:17]

Participants

3

Reactant 2

HCID 7477p-Anisoyl chlorideHCID 588087185-(5-aminomethylfuran-2-yl)-3-ethyl-6-methyl-1H-pyridin-2-one

Product 1

HCID 58808566HCID 58808566, compound

Procedure

Example 269 is substantially repeated except for utilizing 5-(5-aminomethylfuran-2-yl)-3-ethyl-6-methyl-1H-pyridin-2-one and 4-methoxybenzoyl chloride to afford the title compound. MS: m/e=367 (M+H).

Sources & evidence

ORD record
ord-3e730e0efc79473fad52321aba6a94ac
Source dataset
uspto-grants-2012_05
Patent number
US08173682B2

Reaction notes

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