Pyridine-2-carbonyl chloride → HCID 58808745, compound

HRID 1921552Notes

Reaction equation

HRID 1921552 reaction equation
[NH2:1][CH2:2][C:3]1[O:7][C:6]([C:8]2[CH:9]=[C:10]([CH2:16][CH3:17])[C:11](=[O:15])[NH:12][C:13]=2[CH3:14])=[CH:5][CH:4]=1.[N:18]1[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=1[C:24](Cl)=[O:25]>>[CH2:16]([C:10]1[C:11](=[O:15])[NH:12][C:13]([CH3:14])=[C:8]([C:6]2[O:7][C:3]([CH2:2][NH:1][C:24]([C:19]3[CH:20]=[CH:21][CH:22]=[CH:23][N:18]=3)=[O:25])=[CH:4][CH:5]=2)[CH:9]=1)[CH3:17]

Participants

3

Reactant 2

HCID 135034Pyridine-2-carbonyl chlorideHCID 588087185-(5-aminomethylfuran-2-yl)-3-ethyl-6-methyl-1H-pyridin-2-one

Product 1

HCID 58808745HCID 58808745, compound

Procedure

Example 269 is substantially repeated except for utilizing 5-(5-aminomethylfuran-2-yl)-3-ethyl-6-methyl-1H-pyridin-2-one and pyridine-2-carboxylic acid chloride to afford the title compound. MS: m/e=338 (M+H).

Sources & evidence

ORD record
ord-f55bf3d9125345409aaae06631aaacf1
Source dataset
uspto-grants-2012_05
Patent number
US08173682B2

Reaction notes

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