3-Dimethylaminobenzoyl chloride → HCID 58808773, compound

HRID 1921554Notes

Reaction equation

HRID 1921554 reaction equation
[NH2:1][CH2:2][C:3]1[O:7][C:6]([C:8]2[CH:9]=[C:10]([CH2:16][CH3:17])[C:11](=[O:15])[NH:12][C:13]=2[CH3:14])=[CH:5][CH:4]=1.[CH3:18][N:19]([CH3:29])[C:20]1[CH:21]=[C:22]([CH:26]=[CH:27][CH:28]=1)[C:23](Cl)=[O:24]>>[CH3:18][N:19]([CH3:29])[C:20]1[CH:21]=[C:22]([CH:26]=[CH:27][CH:28]=1)[C:23]([NH:1][CH2:2][C:3]1[O:7][C:6]([C:8]2[CH:9]=[C:10]([CH2:16][CH3:17])[C:11](=[O:15])[NH:12][C:13]=2[CH3:14])=[CH:5][CH:4]=1)=[O:24]

Participants

3

Reactant 2

HCID 70103423-Dimethylaminobenzoyl chlorideHCID 588087185-(5-aminomethylfuran-2-yl)-3-ethyl-6-methyl-1H-pyridin-2-one

Product 1

HCID 58808773HCID 58808773, compound

Procedure

Example 269 is substantially repeated except for utilizing 5-(5-aminomethylfuran-2-yl)-3-ethyl-6-methyl-1H-pyridin-2-one and 3-dimethylamino-benzoyl chloride to afford the title compound. MS: m/e=380 (M+H).

Sources & evidence

ORD record
ord-606ff70e47be4ad7a75fd092381af203
Source dataset
uspto-grants-2012_05
Patent number
US08173682B2

Reaction notes

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