N-Acetylsulfanilyl chloride → HCID 58808731, compound

HRID 1921556Notes

Reaction equation

HRID 1921556 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[CH:13]=[C:12]([CH2:14][CH3:15])[C:11](=[O:16])[NH:10][C:9]=2[CH3:17])[CH:5]=[CH:4][CH:3]=1.[C:18]([NH:21][C:22]1[CH:27]=[CH:26][C:25]([S:28](Cl)(=[O:30])=[O:29])=[CH:24][CH:23]=1)(=[O:20])[CH3:19]>>[CH2:14]([C:12]1[C:11](=[O:16])[NH:10][C:9]([CH3:17])=[C:8]([C:6]2[CH:5]=[CH:4][CH:3]=[C:2]([NH:1][S:28]([C:25]3[CH:24]=[CH:23][C:22]([NH:21][C:18](=[O:20])[CH3:19])=[CH:27][CH:26]=3)(=[O:30])=[O:29])[N:7]=2)[CH:13]=1)[CH3:15]

Participants

3

Reactant 2

HCID 8481N-Acetylsulfanilyl chlorideHCID 58808698HCID 58808698, compound

Product 1

HCID 58808731HCID 58808731, compound

Procedure

Example 277 is substantially repeated except for utilizing 6-amino-5′-ethyl-2′-methyl-1′H-[2,3′]bipyridinyl-6′-one and 4-acetylamino-benzenesulfonyl chloride to afford the title compound. MS: m/e=427 (M+H).

Sources & evidence

ORD record
ord-e5b63cd17d7942c08a9ef2eb447f4587
Source dataset
uspto-grants-2012_05
Patent number
US08173682B2

Reaction notes

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