反应详情

A solution of 1.46 g of tert-butyl 4-(1-allyloxycarbonylaminocyclopropyl)benzoate in 10 mL of acetonitrile was combined with 1 g of montmorillonite and refluxed for 3 hours. Then more montmorillonite was added and the mixture was boiled for 4 hours. The suspension was filtered hot, the inorganic material was extracted 3× with hot acetonitrile and filtered off, and the acetonitrile solutions were combined and evaporated down. Residue: 0.8 g of crystals.

1. temperaturerefluxed for 3 hours
2. filtrationThe suspension was filtered hot
3. extractionthe inorganic material was extracted 3× with hot acetonitrile
4. filtrationfiltered off
5. customevaporated down