Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1921848Generated: October 30, 2026

HCID 2727950, compound → (5-Amino-2-morpholinophenyl)methanol

https://huagongshe.com/reaction/1921848

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 2727950HCID 2727950—
CatalystPalladium hydroxideHCID 9942167—
SolventEthanolHCID 702—
Product(5-Amino-2-morpholinophenyl)methanolHCID 2313661684.2%

Reaction Steps

To a solution of (2-morpholin-4-yl-5-nitro-phenyl)-methanol (870 mg) in ethanol (40 mL), palladium hydroxide (87 mg) is added and the mixture is stirred in a Parr-apparatus under hydrogen pressure (10 bars) for 4 hours. The reaction mixture is filtrated over Celite 521, washed with ethanol and concentrated in vacuo to give the title compound (640 mg, 83%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08173656B2
Source datasetuspto-grants-2012_05
ORD IDord-0c8a59f0efd348b79b4d1acb493fd53b
Source noteuspto-grants-2012_05