HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 3-oxopyrrolidine-1-carboxylate → Tert-butyl 3-((7-methoxy-3-(2-(methylamino)pyrimidin-4-yl)naphthalen-1-yl)amino)pyrrolidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 3-oxopyrrolidine-1-carboxylate | HCID 471360 | — |
| Reactant | 4-(4-amino-6-methoxynaphthalen-2-yl)-N-methylpyrimidin-2-amine | HCID 58336395 | — |
| Product | Tert-butyl 3-((7-methoxy-3-(2-(methylamino)pyrimidin-4-yl)naphthalen-1-yl)amino)pyrrolidine-1-carboxylate | HCID 53258407 | — |
Reaction Steps
tert-butyl 3-((7-methoxy-3-(2-(methylamino)pyrimidin-4-yl)naphthalen-1-yl)amino)pyrrolidine-1-carboxylate 147 was synthesized according to General Procedure E utilizing compound 33 and replacing tert-butyl 4-oxopiperidine-1-carboxylate with tert-butyl 3-oxopyrrolidine-1-carboxylate. LCMS: 450 [M+H].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08173808B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-fc6d5a1b5f744a79a04b6872552d6e91 |
| Source note | uspto-grants-2012_05 |