HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 3-oxopiperidine-1-carboxylate → Tert-butyl 3-((7-methoxy-3-(2-(methylamino)pyrimidin-4-yl)naphthalen-1-yl)amino)piperidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 3-oxopiperidine-1-carboxylate | HCID 2756825 | — |
| Reactant | 4-(4-amino-6-methoxynaphthalen-2-yl)-N-methylpyrimidin-2-amine | HCID 58336395 | — |
| Product | Tert-butyl 3-((7-methoxy-3-(2-(methylamino)pyrimidin-4-yl)naphthalen-1-yl)amino)piperidine-1-carboxylate | HCID 58336351 | — |
Reaction Steps
tert-butyl 3-((7-methoxy-3-(2-(methylamino)pyrimidin-4-yl)naphthalen-1-yl)amino)piperidine-1-carboxylate 151 was synthesized according to General Procedure E except compound 33 was used a starting material and replacing tert-butyl 4-oxopiperidine-1-carboxylate with tert-butyl 3-oxopiperidine-1-carboxylate. LCMS: 464 [M+H].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08173808B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-42b8e73fc5ce4a079d3cb9288e570ba5 |
| Source note | uspto-grants-2012_05 |