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HRID1921996

反应详情

EQUATION

反应方程式

HRID 1921996 的结构方程式

REACTANTS

反应物

2
结构：CN(C)CCCN
HCID7993

3-(Dimethylamino)propylamine

C5H14N2

结构：CNc1nccc(-c2cc(NCCCBr)c3cc(OC)ccc3c2)n1
HCID53258165

未命名化合物

PRODUCTS

生成物

1
结构：CNc1nccc(-c2cc(NCCCNCCCN(C)C)c3cc(OC)ccc3c2)n1
HCID67305338

未命名化合物

PROCEDURE

实验过程

N′-[3-({7-methoxy-3-[2-(methylamino)pyrimidin-4-yl]-1-naphthyl}amino)propyl]-N,N-dimethylpropane-1,3-diamine 189 was synthesized according to General Procedure H except in Step 2 4-(4-((3-bromopropyl)amino)-6-methoxynaphthalen-2-yl)-N-methylpyrimidin-2-amine and N1,N1-dimethylpropane-1,3-diamine were used. N′-[3-({7-methoxy-3-[2-(methylamino)pyrimidin-4-yl]-1-naphthyl}amino)propyl]-N,N-dimethylpropane-1,3-diamine 191 was isolated as a red-orange solid. M.p.=142-144° C. LCMS (m/z): 423 [M+H].

WORKUP

后处理

  1. customN′-[3-({7-methoxy-3-[2-(methylamino)pyrimidin-4-yl]-1-naphthyl}amino)propyl]-N,N-dimethylpropane-1,3-diamine 189 was synthesized