Guanidine → HCID 53257950, compound

Participants

Reaction Steps

4-({7-methoxy-3-[2-(methylamino)pyrimidin-4-yl]-1-naphthyl}amino)piperidine-1-carboximidamide was synthesized according to General Procedure A: guanidine formation except 4-(6-methoxy-4-(piperidin-4-ylamino)naphthalen-2-yl)-N-methylpyrimidin-2-amine 150 (0.018 g, 0.050 mmol) was used. The reaction mixture was triturated with ether (10 mL) to obtain 4-({7-methoxy-3-[2-(methylamino)pyrimidin-4-yl]-1-naphthyl}amino)piperidine-1-carboximidamide 204 as a solid (0.007 g). LC/MS (m/z): 406 [M+H].

Provenance & Evidence