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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1922072Generated: October 26, 2026

(3-Amino-4-fluorophenoxy)acetic acid methyl ester → [2-Ethyl-8-fluoro-3-(4-methoxybenzyl)-4-oxo-1,4-dihydroquinolin-5-yloxy]acetic acid methyl ester

https://huagongshe.com/reaction/1922072

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3-Amino-4-fluorophenoxy)acetic acid methyl esterHCID 66717607—
Reactant2-(4-Methoxybenzyl)-3-oxopentanoic acid ethyl esterHCID 67456465—
Product[2-Ethyl-8-fluoro-3-(4-methoxybenzyl)-4-oxo-1,4-dihydroquinolin-5-yloxy]acetic acid methyl esterHCID 67458777—

Reaction Steps

The title compound was prepared by the method of Preparation 1c using (3-amino-4-fluorophenoxy)acetic acid methyl ester and 2-(4-methoxybenzyl)-3-oxopentanoic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08173812B2
Source datasetuspto-grants-2012_05
ORD IDord-c4df454f4d5845d68f1f7764cf72f511
Source noteuspto-grants-2012_05