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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1922080Generated: October 30, 2026

HCID 66717613, compound → [3-(4-Acetylbenzyl)-4-difluoromethoxy-2-ethyl-8-fluoroquinolin-5-yloxy]acetic acid methyl ester

https://huagongshe.com/reaction/1922080

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 66717613HCID 66717613—
ReactantChlorodifluoromethyl acetateHCID 86613376—
Product[3-(4-Acetylbenzyl)-4-difluoromethoxy-2-ethyl-8-fluoroquinolin-5-yloxy]acetic acid methyl esterHCID 66717804—

Reaction Steps

The title compound was prepared by the method of Preparation 1d using [3-(4-acetylbenzyl)-2-ethyl-8-fluoro-4-oxo-1,4-dihydroquinolin-5-yloxy]acetic acid methyl ester and acetic acid chlorodifluoromethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08173812B2
Source datasetuspto-grants-2012_05
ORD IDord-21690162884f4681817f7cc090d0e5a3
Source noteuspto-grants-2012_05