Ethyl 3-oxovalerate → 2-(4-Isobutyrylbenzyl)-3-oxopentanoic acid ethyl ester

HRID 1922104Notes

Reaction equation

HRID 1922104 reaction equation
[CH2:1]([O:3][C:4](=[O:10])[CH2:5][C:6](=[O:9])[CH2:7][CH3:8])[CH3:2].Br[CH2:12][C:13]1[CH:18]=[CH:17][C:16]([C:19](=[O:23])[CH:20]([CH3:22])[CH3:21])=[CH:15][CH:14]=1>>[CH2:1]([O:3][C:4](=[O:10])[CH:5]([CH2:12][C:13]1[CH:18]=[CH:17][C:16]([C:19](=[O:23])[CH:20]([CH3:21])[CH3:22])=[CH:15][CH:14]=1)[C:6](=[O:9])[CH2:7][CH3:8])[CH3:2]

Participants

3

Reactant 2

HCID 78656Ethyl 3-oxovalerateHCID 667072451-(4-Bromomethylphenyl)-2-methylpropan-1-one

Product 1

HCID 674582902-(4-Isobutyrylbenzyl)-3-oxopentanoic acid ethyl ester

Procedure

The title compound was prepared by the method of Preparation 3a using 3-oxopentanoic acid ethyl ester and 1-(4-bromomethylphenyl)-2-methylpropan-1-one.

Sources & evidence

ORD record
ord-380518bb57c14b619247a863ad78caad
Source dataset
uspto-grants-2012_05
Patent number
US08173812B2

Reaction notes

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