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Chlorodifluoromethane → [8-Chloro-4-difluoromethoxy-2-isopropyl-3-(4-pyrazol-1-ylbenzyl)quinolin-5-yloxy]acetic acid methyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Chlorodifluoromethane | HCID 6372 | — |
| 反応物 | [8-Chloro-2-isopropyl-4-oxo-3-(4-pyrazol-1-ylbenzyl)-1,4-dihydroquinolin-5-yloxy]acetic acid methyl ester | HCID 67456771 | — |
| 生成物 | [8-Chloro-4-difluoromethoxy-2-isopropyl-3-(4-pyrazol-1-ylbenzyl)quinolin-5-yloxy]acetic acid methyl ester | HCID 67456768 | — |
反応手順
The title compound was prepared by the method of Preparation 10c using [8-chloro-2-isopropyl-4-oxo-3-(4-pyrazol-1-ylbenzyl)-1,4-dihydroquinolin-5-yloxy]acetic acid methyl ester and chlorodifluoromethane.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08173812B2 |
| 出典データセット | uspto-grants-2012_05 |
| ORD ID | ord-98bdbd7701114e4688e41d721c164976 |
| 出典メモ | uspto-grants-2012_05 |