4-Bromobenzyl bromide → 2-(4-bromobenzyl)-3-oxothiobutyric acid S-tert-butyl ester

HRID 1922134Notes

Reaction equation

HRID 1922134 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8]Br)=[CH:4][CH:3]=1.[C:10]([S:14][C:15](=[O:20])[CH2:16][C:17](=[O:19])[CH3:18])([CH3:13])([CH3:12])[CH3:11]>>[C:10]([S:14][C:15](=[O:20])[CH:16]([CH2:8][C:5]1[CH:6]=[CH:7][C:2]([Br:1])=[CH:3][CH:4]=1)[C:17](=[O:19])[CH3:18])([CH3:13])([CH3:11])[CH3:12]

Participants

3

Reactant 2

HCID 685274-Bromobenzyl bromideHCID 140007Butanethioic acid, 3-oxo-, S-(1,1-dimethylethyl) ester

Product 1

HCID 866423782-(4-bromobenzyl)-3-oxothiobutyric acid S-tert-butyl ester

Procedure

The title compound was prepared by the method of Preparation 11a using 1-bromo-4-bromomethylbenzene and 3-oxothiobutyric acid S-tert-butyl ester.

Sources & evidence

ORD record
ord-919b7c24638b4b019568364e7e9a1942
Source dataset
uspto-grants-2012_05
Patent number
US08173812B2

Reaction notes

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