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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1922142Generated: October 26, 2026

3-Amino-4-fluorophenol → 2-(4-bromobenzyl)-N-(2-fluoro-5-hydroxyphenyl)-3-oxobutyramide

https://huagongshe.com/reaction/1922142

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Amino-4-fluorophenolHCID 13519180—
Reactant2-(4-bromobenzyl)-3-oxothiobutyric acid S-tert-butyl esterHCID 86642378—
Product2-(4-bromobenzyl)-N-(2-fluoro-5-hydroxyphenyl)-3-oxobutyramideHCID 86642380—

Reaction Steps

The title compound was prepared by the method of Preparation 11b using 2-(4-bromobenzyl)-3-oxothiobutyric acid S-tert-butyl ester and 3-amino-4-fluoro-phenol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08173812B2
Source datasetuspto-grants-2012_05
ORD IDord-e9f334a912aa4c3ab883250ea10abfc9
Source noteuspto-grants-2012_05