Ethyl 3-(6-methyl-3-pyridyl)propionate → HCID 10057692, compound

Participants

Reaction Steps

To a suspension of ethyl 3-(6-methyl-3-pyridinyl)propanoate (500 mg, 2.59 mmol) in tetrahydrofuran (15 ml) at 0° C., LiAlH4 (1.42 ml, 2.85 mmol) was added dropwise. When the addition was complete, the ice bath was removed and the reaction stirred at room temperature for 1 hour. Wet THF was added dropwise until a white solid precipitated and the evolution of gas ceased. The solid was filtered off, washed twice with Et2O and the filtrate evaporated under vacuum to afford the title compound (403 mg).

Provenance & Evidence