反应详情

A suspension of compound 2 (0.9211 g, 3.017 mmol) and palladium on carbon (10% wt, 0.092 g) in ethanol (10 mL) was stirred and fitted with a hydrogen balloon overnight. The suspension was filtered through a pad of celite and was rinsed with methanol (100 mL). The crude product was subject to flash chromatography on silica gel 2.5% 2M NH3 methanol/CH2Cl2, which resulted in a light brown solid, compound 3 (0.802 g, 96%).

1. filtrationThe suspension was filtered through a pad of celite
2. washwas rinsed with methanol (100 mL)