HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diflunisal → N-(2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16, 19-hexaenamidoethyl)-2',4'-difluoro-4-hydroxybiphenyl-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diflunisal | HCID 3059 | — |
| Reactant | Edasalonexent | HCID 44626120 | — |
| Product | N-(2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16, 19-hexaenamidoethyl)-2',4'-difluoro-4-hydroxybiphenyl-3-carboxamide | HCID 59193260 | — |
Reaction Steps
N-(2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenamidoethyl)-2′,4′-difluoro-4-hydroxybiphenyl-3-carboxamide was prepared in a similar fashion as N-(2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenamidoethyl)-2-hydroxybenzamide, using the appropriate 2′,4′-difluoro-4-hydroxybiphenyl-3-carboxylic acid starting material. Mass calculated for C37H44F2N2O3=602.75; found: [M+H]+=603.3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08173831B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-5f0439d905a54a8d851f6f6a094df017 |
| Source note | uspto-grants-2012_05 |