HRID1922618

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID164578

4-Trifluoromethylsalicylic acid

C8H5F3O3

$结构：CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)Oc1ccc(-c2ccc(F)cc2F)cc1C(=O)OCC$

HCID59193252

未命名化合物

PRODUCTS

生成物

$结构：CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)Oc1cc(C(F)(F)F)ccc1C(=O)OCC$

HCID59193198

未命名化合物

PROCEDURE

实验过程

Ethyl 2-((4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoyloxy)-4-(trifluoromethyl)benzoate was prepared in a similar fashion as ethyl 4-((4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoyloxy)-2′,4′-difluorobiphenyl-3-carboxylate, using the appropriate 2-hydroxy-4-(trifluoromethyl)benzoic acid starting material. Mass calculated for C32H39F3O4=544.64; found: [M+Na]+=567.3.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-88981ec32da64fd798aba774423c6fe3
来源数据集: uspto-grants-2012_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08173831B2
来源说明: uspto-grants-2012_05

反应 SMILES

[C:1]([O:24][C:25]1[CH:30]=[CH:29][C:28](C2C=CC(F)=CC=2F)=[CH:27][C:26]=1[C:39]([O:41][CH2:42][CH3:43])=[O:40])(=[O:23])[CH2:2][CH2:3]/[CH:4]=[CH:5]\[CH2:6]/[CH:7]=[CH:8]\[CH2:9]/[CH:10]=[CH:11]\[CH2:12]/[CH:13]=[CH:14]\[CH2:15]/[CH:16]=[CH:17]\[CH2:18]/[CH:19]=[CH:20]\[CH2:21][CH3:22].OC1C=C([C:54]([F:57])([F:56])[F:55])C=CC=1C(O)=O>>[C:1]([O:24][C:25]1[CH:30]=[C:29]([C:54]([F:57])([F:56])[F:55])[CH:28]=[CH:27][C:26]=1[C:39]([O:41][CH2:42][CH3:43])=[O:40])(=[O:23])[CH2:2][CH2:3]/[CH:4]=[CH:5]\[CH2:6]/[CH:7]=[CH:8]\[CH2:9]/[CH:10]=[CH:11]\[CH2:12]/[CH:13]=[CH:14]\[CH2:15]/[CH:16]=[CH:17]\[CH2:18]/[CH:19]=[CH:20]\[CH2:21][CH3:22]