HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine, 4-(1,1-dimethylethyl)- → 4-(8-((4-tert-butylpiperidin-1-yl)methyl)-2-chloro-9-methyl-9H-purin-6-yl)morpholine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine, 4-(1,1-dimethylethyl)- | HCID 74661 | — |
| Reactant | 4-(8-(bromomethyl)-2-chloro-9-methyl-9H-purin-6-yl)morpholine | HCID 59603481 | — |
| Product | 4-(8-((4-tert-butylpiperidin-1-yl)methyl)-2-chloro-9-methyl-9H-purin-6-yl)morpholine | HCID 59605988 | 68.1% |
Reaction Steps
4-tert-butylpiperidine (0.45 g) was reacted with 4-(8-(bromomethyl)-2-chloro-9-methyl-9H-purin-6-yl)morpholine (1.0 g) via General Procedure C to yield 4-(8-((4-tert-butylpiperidin-1-yl)methyl)-2-chloro-9-methyl-9H-purin-6-yl)morpholine (0.80 g) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08173650B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-98cf440d6ec740b68870de5e70da2daf |
| Source note | uspto-grants-2012_05 |