HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N-Dimethyl-1H-benzimidazol-2-amine → HCID 59605870, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N-Dimethyl-1H-benzimidazol-2-amine | HCID 17846 | — |
| Reactant | 2-(1-((2-chloro-9-methyl-6-morpholino-9H-purin-8-yl)methyl)piperidin-4-yl)propan-2-ol | HCID 59603426 | — |
| Product | HCID 59605870 | HCID 59605870 | — |
Reaction Steps
Following General Procedure I for Buchwald coupling, 2-(1-((2-chloro-9-methyl-6-morpholino-9H-purin-8-yl)methyl)piperidin-4-yl)propan-2-ol and N,N-dimethyl-1H-benzo[d]imidazol-2-amine were reacted to give 188. LCMS m/z: 534.3 (MH+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08173650B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-b3f43567067740e9a0fa6ce1aa016d14 |
| Source note | uspto-grants-2012_05 |