Acetic Acid → HCID 59605739, compound

HRID 1922956Notes

Reaction equation

HRID 1922956 reaction equation
Cl[C:2]1[N:10]=[C:9]2[C:5]([N:6]=[C:7]([CH2:12][N:13]3[CH2:18][CH:17]([CH3:19])[O:16][CH:15]([CH3:20])[CH2:14]3)[N:8]2[CH3:11])=[C:4]([N:21]2[CH2:26][CH2:25][O:24][CH2:23][CH2:22]2)[N:3]=1.[C:27]1([NH2:34])[C:28]([NH2:33])=[CH:29][CH:30]=[CH:31][CH:32]=1.[C:35](O)(=O)[CH3:36]>>[CH3:20][CH:15]1[O:16][CH:17]([CH3:19])[CH2:18][N:13]([CH2:12][C:7]2[N:8]([CH3:11])[C:9]3[C:5]([N:6]=2)=[C:4]([N:21]2[CH2:26][CH2:25][O:24][CH2:23][CH2:22]2)[N:3]=[C:2]([N:33]2[C:28]4[CH:29]=[CH:30][CH:31]=[CH:32][C:27]=4[N:34]=[C:35]2[CH3:36])[N:10]=3)[CH2:14]1

Participants

4

Reactant 3

HCID 176Acetic AcidHCID 7243O-PhenylenediamineHCID 86648243HCID 86648243, compound

Product 1

HCID 59605739HCID 59605739, compound

Procedure

Following the procedures for 157 and General Procedure J, where in Step 1, 4-((2-chloro-9-methyl-6-morpholino-9H-purin-8-yl)methyl)-2,6-dimethylmorpholine and benzene-1,2-diamine were reacted, followed by condensation with acetic acid to give 194. LCMS m/z: 477.2 (MH+)

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-809aa9d5ca1d480aac0e5556391744e7
Source dataset
uspto-grants-2012_05
Patent number
US08173650B2

Reaction notes

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