HuagongsheHuagongshe Chemistry Print Report · For research reference only
4,4-Difluoropiperidine → HCID 59605383, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4,4-Difluoropiperidine | HCID 2758352 | — |
| Reactant | 4-(8-(bromomethyl)-9-methyl-2-(2-methyl-1H-benzo[d]imidazol-1-yl)-9H-purin-6-yl)morpholine | HCID 59605812 | — |
| Product | HCID 59605383 | HCID 59605383 | — |
Reaction Steps
4-(8-(bromomethyl)-9-methyl-2-(2-methyl-1H-benzo[d]imidazol-1-yl)-9H-purin-6-yl)morpholine (50 mg) was reacted with 4,4-difluoropiperidine via General Procedure E to give 19.3 mg of 278 following reverse phase purification. MS (Q1) 483.2 (M)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08173650B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-421d10feb4c2476d921b679845bb3d97 |
| Source note | uspto-grants-2012_05 |