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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1923055Generated: October 30, 2026

2-(1-((2-chloro-9-methyl-6-morpholino-9H-purin-8-yl)methyl)piperidin-4-yl)propan-2-ol → HCID 59605279, compound

https://huagongshe.com/reaction/1923055

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(1-((2-chloro-9-methyl-6-morpholino-9H-purin-8-yl)methyl)piperidin-4-yl)propan-2-olHCID 59603426—
ReactantHCID 67492250HCID 67492250—
ProductHCID 59605279HCID 59605279—

Reaction Steps

Following General Procedure I for Buchwald coupling, 2-(1-((2-chloro-9-methyl-6-morpholino-9H-purin-8-yl)methyl)piperidin-4-yl)propan-2-ol and 2-(1-fluorocyclopropyl)-1H-benzimidazole were reacted to give 307. LCMS m/z: 549.3 (MH+)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08173650B2
Source datasetuspto-grants-2012_05
ORD IDord-11f8e002a2c240a3babe39cc0b64e96e
Source noteuspto-grants-2012_05